7 Mar Learn the causes of difficult urination and the medications used in treatment. Common causes include UTI, benign prostatic hyperplasia, and prostate cancer. Pinpoint your symptoms and signs with MedicineNet's Symptom Checker. 18 Oct Painful urination is a broad term that describes discomfort during urination. This pain may originate in the bladder, urethra, or perineum. The urethra is the tube that carries urine outside of your body. In men, the area between the scrotum and . 11 Jan Burning pee is the worst. Only a few things should be happening when you pee, and almost bursting into tears isn't one of them. Ridding your body of waste via your urine? Sure. Wondering why all people with vaginas don't get the luxury of peeing standing up, thus avoiding any toilet seat germs (as.